Biliary Schwannoma That Required Differentiation from Bile Duct Cancer

Schwannomas are benign tumors originating from Schwann cells, which the main component of neural sheath. Biliary schwannomas extremely rare. We report case a 78-year-old man who presented with no abdominal symptoms or jaundice. CT imaging showed hyperdense mass extending along extrahepatic bile duct, and upstream ducts were dilated. performed duct resection under preoperative diagnosis cancer. A histopathological examination resected specimen revealed that tumor consisted spindle cells exhibited palisading arrangement. Immunohistochemical staining was positive for protein S-100 vimentin. Based on these pathological findings, we diagnosed patient schwannoma duct. Our search relevant literature 19 studies biliary schwannomas. In our case, surgical findings noninvasive mobile. During surgery, fast frozen section analysis performed, malignant observed. These results enabled us to avoid major hepatectomy. experienced difficult distinguish